The pregnancy link to childhood allergies

Using data from the Global Burden of Disease database, which covers nearly 200 countries, the research has found children aged 1 to 4 years are significantly more susceptible to developing eczema and asthma if their mothers had maternal hypertensive disorders (MHD), such as preeclampsia or gestational hypertension during pregnancy.

"Understanding the links between MHD and childhood allergies is crucial for improving long-term health outcomes for children,” says Professor Nanan, paediatrician and researcher at Nepean Hospital.

“By exploring the impacts of maternal health on immune development, we can pave the way for targeted interventions that protect our children from allergic diseases."

The research reveals that while the impact of MHD on allergic disease development is most pronounced during early childhood, these associations tend to weaken as children grow older.

This suggests that other factors, such as environmental influences and nutrition, may play a larger role later in life.

"We need to focus on early maternal health influences but also look into environmental and nutritional factors that come into play as children develop."

Professor Nanan emphasises the need for further research to explore additional factors that might influence the development of allergic diseases in children.

"As we deepen our understanding of these connections, we will be better equipped to improve health outcomes for mothers and their children."

The research team also included scientists and clinicians from Nepean Hospital and the University of Sydney.